US 12,290,785 B2
Tangential flow filter system for the filtration of materials from biologic fluids
Emily Rolfes Meyering, St. Louis Park, MN (US); Gary Seim, Minneapolis, MN (US); Abhi Vase, Los Altos Hills, CA (US); Ben Krehbiel, Lake City, MN (US); Blake Hedstrom, Minneapolis, MN (US); Aaron McCabe, Edina, MN (US); and Jack Mondry, Edina, MN (US)
Assigned to MINNETRONIX, INC.
Filed by MINNETRONIX, INC., St. Paul, MN (US)
Filed on Dec. 15, 2022, as Appl. No. 18/082,152.
Application 16/851,575 is a division of application No. 15/229,392, filed on Aug. 5, 2016, granted, now 10,632,237, issued on Apr. 28, 2020.
Application 18/082,152 is a continuation of application No. 16/851,575, filed on Apr. 17, 2020, granted, now 11,529,452.
Claims priority of provisional application 62/201,287, filed on Aug. 5, 2015.
Prior Publication US 2023/0120296 A1, Apr. 20, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. B01D 61/58 (2006.01); A61M 1/00 (2006.01); A61M 25/00 (2006.01); A61M 27/00 (2006.01); B01D 61/14 (2006.01); B01D 61/32 (2006.01)
CPC B01D 61/58 (2013.01) [A61M 1/88 (2021.05); A61M 1/884 (2021.05); A61M 25/00 (2013.01); B01D 61/145 (2013.01); B01D 61/147 (2013.01); B01D 61/149 (2022.08); B01D 61/32 (2013.01); A61M 27/006 (2013.01); A61M 2202/0464 (2013.01); A61M 2205/3327 (2013.01); A61M 2205/3334 (2013.01); A61M 2205/75 (2013.01); A61M 2206/11 (2013.01); A61M 2230/005 (2013.01); B01D 2311/12 (2013.01); B01D 2311/16 (2013.01); B01D 2313/12 (2013.01); B01D 2313/18 (2013.01); B01D 2315/08 (2013.01); B01D 2315/10 (2013.01); B01D 2317/022 (2013.01); B01D 2317/04 (2013.01); B01D 2317/08 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A system for removing materials from cerebrospinal fluid (CSF) of a human or animal fluid (CSF) of a human or animal subject, the system comprising:
a filtration subsystem configured to withdraw a volume of cerebrospinal fluid from the human or animal subject, filter the withdrawn volume of cerebrospinal fluid into a volume of permeate and a volume of retentate, filter the volume of retentate into a second volume of permeate and a second volume of retentate, return the volume of permeate and the second volume of permeate to the human or animal subject, and direct the second volume of retentate to a waste container; and
a plurality of sensors, cooperating with a processor located and configured to generate and receive data, including during filtration of the fluid through the filtration subsystem, indicating the volume of cerebrospinal fluid withdrawn from the human or animal subject, generate and receive data indicating the volume of permeate returned to the human or animal subject, generate and receive data indicating the flow volume of second permeate returned to the human or animal subject, and calculate a waste rate of the system, wherein the waste rate is the difference between the volume of fluid withdrawn from the subject and the flow volume of returned permeate returned to the subject combined with the returned volume of second permeate returned to the subject over a period of time.