	US 12,290,702 B2
	Wet preparation of radiotherapy sources
Michael Schmidt, Kfar Saba (IL); and Itzhak Kelson, Tel Aviv (IL)
Assigned to Alpha Tau Medical Ltd, Jerusalem (IL)
Filed by ALPHA TAU MEDICAL LTD., Tel Aviv (IL)
Filed on Nov. 8, 2020, as Appl. No. 17/092,269.
Application 17/092,269 is a continuation of application No. PCT/IB2020/059317, filed on Oct. 5, 2020.
Claims priority of provisional application 62/913,184, filed on Oct. 10, 2019.
Prior Publication US 2021/0128945 A1, May 6, 2021
Int. Cl. A61N 5/10 (2006.01); A61K 51/02 (2006.01); A61K 51/12 (2006.01); G21G 4/10 (2006.01)

CPC A61N 5/1014 (2013.01) [A61K 51/025 (2013.01); A61K 51/1282 (2013.01); G21G 4/10 (2013.01); A61N 2005/1024 (2013.01); A61N 2005/1085 (2013.01)]

19 Claims

1. A method of accumulating radium radionuclides, comprising:

providing a first solution including thorium radionuclides and a thorium-binding extractant, wherein the first solution does not bind to radium, such that radium atoms resulting from decay of the thorium diffuse out of the first solution;

allowing a portion of the thorium radionuclides in the first solution to decay into radium atoms;

allowing the radium atoms to diffuse out of the first solution; and

collecting radium atoms resulting from the decay that diffused out of the first solution, from out of the first solution,

wherein providing the first solution comprises introducing the first solution into a chamber with a second solution, which does not mix with the first solution, such that the decay radium atoms diffuse into the second solution, and

wherein the first solution is lighter than the second solution.