US 12,290,666 B2
Drug delivery devices with partial needle retraction
Ali Nekouzadeh, Simi Valley, CA (US); Carl Conrath, Thousand Oaks, CA (US); and Basel Hasan Taha, Simi Valley, CA (US)
Assigned to AMGEN INC., Thousand Oaks, CA (US)
Appl. No. 17/277,555
Filed by AMGEN INC., Thousand Oaks, CA (US)
PCT Filed Oct. 22, 2019, PCT No. PCT/US2019/057370
§ 371(c)(1), (2) Date Mar. 18, 2021,
PCT Pub. No. WO2020/092056, PCT Pub. Date May 7, 2020.
Claims priority of provisional application 62/754,362, filed on Nov. 1, 2018.
Prior Publication US 2022/0031953 A1, Feb. 3, 2022
Int. Cl. A61M 5/315 (2006.01); A61M 5/20 (2006.01)
CPC A61M 5/31511 (2013.01) [A61M 5/2033 (2013.01); A61M 5/31501 (2013.01)] 12 Claims
OG exemplary drawing
 
1. A drug delivery device comprising:
an outer casing including one or more sidewalls, a distal end wall, and a proximal end wall defining an interior, the distal end wall having an opening extending therethrough;
a primary container assembly at least partially received within the interior of the outer casing, the primary container assembly including a reservoir having a sidewall defining an interior containing a drug to be expelled, a plunger stopper disposed within the interior of the reservoir to expel the drug therefrom, and a drug delivery member operably connected to the reservoir and configured to be fluidly coupled to the interior thereof, at least the drug delivery member being movable between first and second positions with respect to the outer casing; and
a resilient member disposed between the primary container assembly and the outer casing, wherein upon moving the drug delivery member to the second position in which the delivery member is driven through the opening and prior to the plunger stopper expelling the drug from the interior of the reservoir, the resilient member is in a deformed state that biases the drug delivery member to move in a retraction direction toward the first position to partially retract the drug delivery member to a retracted position, whereby the plunger stopper expels the drug from the interior of the reservoir while the drug delivery member is in the retracted position.