US 12,290,663 B2
Front loaded auto injector for administering a medicament
Paul Erik Fabricius, Holstebro (DK); Jan Olesen, Holstebro (DK); Steen Jensen, Dragør (DK); Henrik Egesborg, Hellerup (DK); and Per Mølgaard Pedersen, Struer (DK)
Assigned to Ascendis Pharma A/S, Hellerup (DK)
Filed by Ascendis Pharma A/S, Hellerup (DK)
Filed on Feb. 21, 2023, as Appl. No. 18/112,265.
Application 18/112,265 is a continuation of application No. 16/060,630, granted, now 11,607,496, previously published as PCT/EP2016/082858, filed on Dec. 29, 2016.
Claims priority of application No. 15203168 (EP), filed on Dec. 30, 2015; and application No. 16190461 (EP), filed on Sep. 23, 2016.
Prior Publication US 2023/0270945 A1, Aug. 31, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61M 5/20 (2006.01); A61M 5/24 (2006.01); A61M 5/315 (2006.01); A61M 5/32 (2006.01)
CPC A61M 5/2066 (2013.01) [A61M 5/20 (2013.01); A61M 5/24 (2013.01); A61M 5/31511 (2013.01); A61M 5/31573 (2013.01); A61M 5/31576 (2013.01); A61M 5/326 (2013.01); A61M 2005/2411 (2013.01); A61M 2005/31588 (2013.01); A61M 2005/3267 (2013.01); A61M 2205/332 (2013.01); A61M 2205/3368 (2013.01); A61M 2205/50 (2013.01); A61M 2205/502 (2013.01); A61M 2205/6063 (2013.01); A61M 2205/82 (2013.01); A61M 2205/8206 (2013.01)] 35 Claims
OG exemplary drawing
 
1. An auto injector for preparing or administering a medicament from a cartridge having a first cartridge end and a second cartridge end and having a cartridge outlet at the first cartridge end, the cartridge comprising a cartridge compartment with a first cartridge subcompartment containing a first medicament component of the medicament and a second cartridge subcompartment containing a second medicament component of the medicament, the auto injector comprising:
a housing;
a cartridge receiver with a cartridge receiver opening, the cartridge receiver being configured to receive the cartridge by insertion of the second end of the cartridge through the cartridge receiver opening;
a code sensor configured to detect reception of the cartridge in the cartridge receiver and provide a cartridge detection signal indicative of the cartridge being received in the cartridge receiver, read a cartridge code feature and provide a code signal indicative of the cartridge code feature;
a drive module coupled to move a plunger rod between a retracted plunger rod position and an extended plunger rod position, the plunger rod being configured to move a first stopper;
an orientation sensor configured to provide an orientation signal indicative of the orientation of the cartridge when received in the cartridge receiver; and
a processing unit coupled to the orientation sensor, the code sensor, and to the drive module;
the processing unit being configured to:
receive a first input signal;
receive the cartridge detection signal;
receive the code signal;
receive the orientation signal;
control the drive module to move the plunger rod to a mix plunger rod position following reception of the cartridge detection signal and the first input signal; and
control the drive module to move the plunger rod to a prime plunger rod position following completion of movement of the plunger rod to the mix plunger rod position, wherein movement of the plunger rod to the mix plunger rod position and/or the prime plunger rod position and/or an injection plunger rod position is based on the code signal.