US 12,290,608 B2
Layered collagen dressing with extended bacteria and biofilm reducing capabilities
Kathleen L. Derrick, San Antonio, TX (US); and Kristine M. Kieswetter, San Antonio, TX (US)
Assigned to Solventum Intellectual Properties Company, Maplewood, MN (US)
Appl. No. 17/623,432
Filed by Solventum Intellectual Properties Company, Maplewood, MN (US)
PCT Filed Jun. 25, 2020, PCT No. PCT/IB2020/056046
§ 371(c)(1), (2) Date Dec. 28, 2021,
PCT Pub. No. WO2020/261190, PCT Pub. Date Dec. 30, 2020.
Claims priority of provisional application 62/868,639, filed on Jun. 28, 2019.
Prior Publication US 2022/0347339 A1, Nov. 3, 2022
Int. Cl. A61L 15/20 (2006.01); A61K 31/194 (2006.01); A61L 15/18 (2006.01); A61L 15/22 (2006.01); A61L 15/42 (2006.01); A61L 15/44 (2006.01); A61L 15/64 (2006.01)
CPC A61L 15/20 (2013.01) [A61K 31/194 (2013.01); A61L 15/18 (2013.01); A61L 15/225 (2013.01); A61L 15/42 (2013.01); A61L 15/44 (2013.01); A61L 15/64 (2013.01); A61L 2300/104 (2013.01); A61L 2300/21 (2013.01); A61L 2300/404 (2013.01); A61L 2300/802 (2013.01)] 16 Claims
 
1. A wound dressing composition comprising a first layer and a second layer:
wherein the first layer comprises a homogeneous mixture of a collagen, an oxidized cellulose, and at least one bacteria reducing active ingredient;
wherein the second layer comprises a homogeneous mixture of a collagen, an oxidized cellulose, a silver compound, and at least one bacteria reducing active ingredient;
wherein the at least one bacteria reducing active ingredient of each of the first layer and of the second layer is citric acid,
wherein the at least one bacterial reducing active ingredient of each of the first layer and the second layer is mixed with a solvent, wherein the solvent consists of ethanol, and
wherein the first layer and the second layer are each in the form of a freeze-dried sponge.