US 12,290,591 B2
Fragrance compositions
Addi Fadel, Plainsboro, NJ (US); Valery Normand, Plainsboro, NJ (US); Artem Kirshon, Plainsboro, NJ (US); Nicholas O'Leary, Plainsboro, NJ (US); and Arnaud Struillou, Satigny (CH)
Assigned to FIRMENICH SA, Satigny (CH)
Appl. No. 17/426,168
Filed by Firmenich SA, Satigny (CH)
PCT Filed May 15, 2020, PCT No. PCT/EP2020/063612
§ 371(c)(1), (2) Date Jul. 28, 2021,
PCT Pub. No. WO2020/234154, PCT Pub. Date Nov. 26, 2020.
Claims priority of provisional application 62/849,558, filed on May 17, 2019.
Claims priority of application No. 19201721 (EP), filed on Oct. 2, 2019.
Prior Publication US 2022/0096355 A1, Mar. 31, 2022
Int. Cl. A61K 8/86 (2006.01); A61K 8/34 (2006.01); A61Q 5/00 (2006.01); A61Q 13/00 (2006.01); A61Q 19/00 (2006.01)
CPC A61K 8/86 (2013.01) [A61K 8/34 (2013.01); A61K 8/342 (2013.01); A61Q 5/00 (2013.01); A61Q 13/00 (2013.01); A61Q 19/00 (2013.01)] 16 Claims
 
1. A composition:
wherein the composition comprises:
a. ethanol, in an amount from 30 to 75 wt % relative to the total weight of the composition;
b. a fragrance component present in an amount from 0.04 to 40 wt %, relative to the total weight of the composition,
wherein the fragrance component comprises:
i. a high volatility component an amount from 0.08 to 55 wt % of the fragrance component, comprising
a. a first at least one perfume raw material having a first vapor pressure greater than 0.08 Torr at 22° C.; and optionally
b. a second at least one perfume raw material having a first vapor pressure greater than 0.08 Torr at 22° C.;
ii. a medium volatility component in an amount from 0.08 to 85 wt % of the fragrance component, comprising:
a. a first at least one perfume raw material having a first vapor pressure range of 0.0008 to 0.08 Torr at 22° C.; and optionally
b. a second at least one perfume raw material having a first vapor pressure range of 0.0008 to 0.08 Torr at 22° C.; and
c. at least one modulator selected from the group consisting of: dodecanol; 3-Methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pentan-2-ol; (E)-1,2-Dimethoxy-4-(prop-1-en-1-yl)benzene; Cyclopentadecanone; 3,7,11-trimethyl-1,6,10-dodecatrien-3-ol; 6,10-Dimethyl-3-oxa-9-undecenal; (4E,8E)-1,5,9-trimethyl-13-oxabicyclo[10.1.0]trideca-4,8-diene; 6-[(E)-pent-2-enyl]oxan-2-one; Aceticacid,(1-oxopropoxy)-, 1-(3,3-dimethylcyclohexyl) ethyl; 4-α,5-Dimethyl-1,2,3,4,4α,5,6,7-octahydro-7-keto-3-isopropenylnaphthalene; (+-)-(1E)-1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-1,6-heptadien-3-one (A); (1E)-1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1,6-heptadien-3-one (B); Methyl 2-(3-oxo-2-pentylcyclopentyl) ethanoate; hexyl 2-hydroxybenzoate; oxacyclohexadecan-2-one; 3-methylcyclopentadecan-1-one; cyclopentadec-4-en-1-one; (8E)-1-oxacycloheptadec-8-en-2-one; methyl 2-[(1R,2S)-3-oxo-2-pentylcyclopentyl]acetate; methyl 2-[(1R,2R)-3-oxo-2-[(Z)-pent-2-enyl]cyclopentyl]acetate; 4,6,6,7,8,8-hexamethyl-1,3,4,7-tetrahydrocyclopenta[g]isochromene; 6-heptyloxan-2-one; benzyl benzoate; (2E)-2-benzylideneheptanal; (2E)-2-benzylideneoctanal; (9Z)-cycloheptadec-9-en-1-one; propan-2-yl tetradecanoate; and combinations thereof;
in an amount from 5.0 to 20 wt %, relative to the total weight of the composition;
wherein the first vapor pressure of the at least one first perfume raw material of the high volatility component is determined in the absence of the at least one modulator;
wherein the first vapor pressure of the at least one second perfume raw material of the high volatility component is determined in the absence of the at least one modulator;
wherein the at least one modulator changes the first vapor pressure of the at least one second perfume raw material of the high volatility component to a second vapor pressure;
wherein the second vapor pressure of the at least one second perfume raw material of the high volatility component is in the range of 0.0008 to 0.08 Torr at 22° C.;
wherein the first vapor pressure range of the at least one first perfume raw material of the medium volatility component is determined in the absence of the at least one modulator;
wherein the first vapor pressure range of the at least one second perfume raw material of the medium volatility component is determined in the absence of the at least one modulator;
wherein the at least one modulator changes the first vapor pressure range of the at least one second perfume raw material of the medium volatility component to a second vapor pressure; and
wherein the second vapor pressure of the at least one second perfume raw material of the medium volatility component is less than 0.0008 Torr at 22° C.