US 12,290,564 B2
Methods and apparatuses for treating tumors
Ramtin Agah, Menlo Park, CA (US); Kamran Najmabadi, Palo Alto, CA (US); Shaun Bagai, Mountain View, CA (US); and Joseph F. Paraschac, Campbell, CA (US)
Assigned to RenovoRx, Inc., Mountain View, CA (US)
Filed by RenovoRx, Inc., Mountain View, CA (US)
Filed on May 7, 2021, as Appl. No. 17/315,220.
Application 17/315,220 is a continuation in part of application No. 16/685,974, filed on Nov. 15, 2019, granted, now 11,052,224.
Application 16/685,974 is a continuation of application No. PCT/US2018/033482, filed on May 18, 2018.
Application PCT/US2018/033482 is a continuation in part of application No. 15/807,011, filed on Nov. 8, 2017, granted, now 10,695,543, issued on Jun. 30, 2020.
Claims priority of provisional application 62/507,962, filed on May 18, 2017.
Prior Publication US 2021/0268107 A1, Sep. 2, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 90/00 (2016.01); A61K 31/166 (2006.01); A61K 31/167 (2006.01); A61K 31/175 (2006.01); A61K 31/282 (2006.01); A61K 31/337 (2006.01); A61K 31/404 (2006.01); A61K 31/407 (2006.01); A61K 31/436 (2006.01); A61K 31/4745 (2006.01); A61K 31/495 (2006.01); A61K 31/502 (2006.01); A61K 31/513 (2006.01); A61K 31/519 (2006.01); A61K 31/573 (2006.01); A61K 31/704 (2006.01); A61K 31/7068 (2006.01); A61K 33/243 (2019.01); A61K 35/28 (2015.01); A61K 38/15 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61K 51/04 (2006.01); A61M 25/00 (2006.01); A61M 25/10 (2013.01); A61M 31/00 (2006.01); A61N 5/10 (2006.01)
CPC A61K 39/3955 (2013.01) [A61B 90/39 (2016.02); A61K 31/166 (2013.01); A61K 31/167 (2013.01); A61K 31/175 (2013.01); A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/404 (2013.01); A61K 31/407 (2013.01); A61K 31/436 (2013.01); A61K 31/4745 (2013.01); A61K 31/495 (2013.01); A61K 31/502 (2013.01); A61K 31/513 (2013.01); A61K 31/519 (2013.01); A61K 31/573 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61K 33/243 (2019.01); A61K 35/28 (2013.01); A61K 38/15 (2013.01); A61K 39/0011 (2013.01); A61K 45/06 (2013.01); A61K 51/0482 (2013.01); A61M 25/007 (2013.01); A61M 25/1011 (2013.01); A61M 31/005 (2013.01); A61N 5/10 (2013.01); A61B 2090/3933 (2016.02); A61M 2025/1015 (2013.01); A61M 2025/1052 (2013.01); A61M 2205/3331 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A method, comprising:
treating a target area including a tumor to reduce a microvasculature in the target area;
inserting a catheter device into a lumen within or adjacent to the tumor, the catheter device including a first occluder and a second occluder;
isolating a segment of the lumen proximate to the target area using the first occluder and the second occluder;
delivering a dose of an agent to the target area having the reduced microvasculature from the isolated segment via the catheter device.