	US 12,290,512 B2
	Gel composition with an anaesthetic effect of short and long term duration
José António Pacheco Dos Santos Dias, Lisbon (PT)
Appl. No. 17/418,858
Filed by José António Pacheco Dos Santos Dias, Lisbon (PT)
PCT Filed Dec. 17, 2019, PCT No. PCT/IB2019/060920 § 371(c)(1), (2) Date Jun. 28, 2021, PCT Pub. No. WO2020/136502, PCT Pub. Date Jul. 2, 2020.
Claims priority of application No. 115231 (PT), filed on Dec. 27, 2018.
Prior Publication US 2022/0071973 A1, Mar. 10, 2022
Int. Cl. A61K 31/445 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 31/155 (2006.01); A61K 31/167 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/14 (2017.01); A61K 47/38 (2006.01); A61P 23/02 (2006.01)

CPC A61K 31/445 (2013.01) [A61K 9/0034 (2013.01); A61K 9/06 (2013.01); A61K 31/155 (2013.01); A61K 31/167 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/14 (2013.01); A61K 47/38 (2013.01); A61P 23/02 (2018.01)]

16 Claims

1. A gel composition with an anaesthetic effect of short and long term duration for administration through the urethra characterized in that it comprises a lubricant gel, at least one local short duration anaesthetic composition and at least one local long duration anaesthetic composition, the local long duration anaesthetic composition comprising ropivacaine and/or bupivacaine, the ratio between the w/w percentage of the local long duration and short anaesthetic compositions being such that the effect of the local long duration anaesthetic composition overlaps with the effect of the local short duration anaesthetic composition.