US 12,290,489 B2
Systems and methods for cryostorage bag protection
Brian Schryver, Redwood City, CA (US)
Assigned to BioLife Solutions, Inc., Bothell, WA (US)
Appl. No. 17/046,502
Filed by BioLife Solutions, Inc., Bothell, WA (US)
PCT Filed Apr. 11, 2019, PCT No. PCT/US2019/027047
§ 371(c)(1), (2) Date Oct. 9, 2020,
PCT Pub. No. WO2019/200145, PCT Pub. Date Oct. 17, 2019.
Claims priority of provisional application 62/655,895, filed on Apr. 11, 2018.
Prior Publication US 2021/0137787 A1, May 13, 2021
Int. Cl. A61J 1/10 (2006.01); A01N 1/02 (2006.01); A61J 1/16 (2023.01); B65D 81/38 (2006.01); F25C 1/22 (2018.01); F25D 3/10 (2006.01); F25D 25/00 (2006.01)
CPC A61J 1/10 (2013.01) [A01N 1/0284 (2013.01); A61J 1/165 (2013.01); B65D 81/3816 (2013.01); F25C 1/22 (2013.01); F25D 3/10 (2013.01); F25D 25/00 (2013.01); F25D 2303/084 (2013.01)] 28 Claims
OG exemplary drawing
 
1. A system for protecting a cryostorage bag, said system comprising:
a protective interface cushion device, comprising:
an upper half having a first interior surface configured to receive a first side of a cryostorage bag, said upper half further comprising a first outer surface;
a lower half having a second interior surface configured to receive a second side of a cryostorage bag, wherein said first side is opposite said second side, said lower half further comprising a second outer surface, wherein said upper and lower halves are secured together to provide an exterior dimension;
a cutout forming an opening through at least one of the first interior surface, the first outer surface, the second interior surface, and the second outer surface, wherein said cutout is configured to restrict a first fill volume of a cryostorage bag during a freezing procedure;
a recessed surface provided on at least one of the first interior surface and the second interior surface, wherein said recessed surface is configured to restrict a second fill volume of a cryostorage bag during a freezing procedure; and
an exclusion region between the first interior surface and the second interior surface, the exclusion region configured to displace liquid contents of the cryostorage bag into the first fill volume and/or the second fill volume; and
a protective shell, comprising:
a lid having an upper interior surface configured to compatibly receive the first outer surface; and
a tray having a lower interior surface configured to compatibly receive the second outer surface, wherein when the lid and tray are secured together an interior dimension of the protective shell is approximately equal to the exterior dimension of the protective interface cushion device.