US 12,290,380 B1
Method and system to monitor urine output and manage fluid retention in a patient
Howard Levin, Teaneck, NY (US); Andrew Halpert, Brookline, MA (US); and Mark Gelfand, New York, NY (US)
Assigned to Reprieve Cardiovascular, Inc., Milford, MA (US)
Filed by Reprieve Cardiovascular, Inc., Milford, MA (US)
Filed on Aug. 20, 2019, as Appl. No. 16/544,975.
Claims priority of provisional application 62/720,009, filed on Aug. 20, 2018.
Int. Cl. A61B 5/00 (2006.01); A61B 5/0295 (2006.01); A61B 5/20 (2006.01); A61M 5/172 (2006.01); A61M 25/00 (2006.01)
CPC A61B 5/4839 (2013.01) [A61B 5/0295 (2013.01); A61B 5/208 (2013.01); A61M 5/1723 (2013.01); A61M 25/0017 (2013.01); A61M 2202/0496 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A method to reduce liquid levels of a patient, the method comprising:
monitoring urine output by the patient;
infusing a hydration liquid configured to prevent or treat dehydration into the patient;
determining a net rate of liquid removal from the patient based on a difference between the urine output and the infusion of the hydration liquid,
obtaining a first intravascular volume level of the patient that corresponds to a baseline intravascular volume level;
obtaining a second intravascular volume level of the patient that corresponds to an at risk intravascular volume level;
during a first period, causing the infusion of the hydration liquid at a first hydration rate greater than a rate of the urine output to reduce an intravascular fluid volume of the patient, and
during a second period after the rate of the urine output reaches or exceeds a predetermined urine output threshold, adjusting the infusion of the hydration liquid to be a second hydration rate different than the first hydration rate and less than the rate of the urine output, wherein, during the second period, the intravascular fluid volume of the patient remains between the first intravascular volume level and the second intravascular volume level.