US 12,290,350 B2
Oxygen consumption and energy expenditure monitoring
Peter Clemensen, Odense (DK); John Kheir, Charlestown, MA (US); Brian Polizzotti, Swampscott, MA (US); and Arne Bo Thomsen, Tommerup (DK)
Assigned to Children's Medical Center Corporation, Boston, MA (US); and COSMED S.r.l., Rome (IT)
Appl. No. 16/762,456
Filed by Children's Medical Center Corporation, Boston, MA (US); and COSMED S.r.l., Rome (IT)
PCT Filed Nov. 9, 2018, PCT No. PCT/US2018/059961
§ 371(c)(1), (2) Date May 7, 2020,
PCT Pub. No. WO2019/094680, PCT Pub. Date May 16, 2019.
Claims priority of provisional application 62/583,927, filed on Nov. 9, 2017.
Prior Publication US 2020/0359935 A1, Nov. 19, 2020
Int. Cl. A61B 5/083 (2006.01); A61B 5/00 (2006.01); A61B 5/08 (2006.01); A61B 5/087 (2006.01); A61B 5/097 (2006.01); A61M 16/00 (2006.01); A61M 16/08 (2006.01); A61M 16/10 (2006.01); A61M 16/12 (2006.01); A61M 16/16 (2006.01); A61M 16/20 (2006.01); G09B 23/28 (2006.01); G09B 23/30 (2006.01)
CPC A61B 5/0833 (2013.01) [A61B 5/0816 (2013.01); A61B 5/0836 (2013.01); A61B 5/087 (2013.01); A61B 5/097 (2013.01); A61B 5/4836 (2013.01); A61B 5/742 (2013.01); A61M 16/024 (2017.08); A61M 16/0833 (2014.02); A61M 16/085 (2014.02); A61M 16/202 (2014.02); A61B 2503/045 (2013.01); A61M 2016/003 (2013.01); A61M 2016/1025 (2013.01); A61M 16/1055 (2013.01); A61M 16/16 (2013.01); A61M 2202/0208 (2013.01); A61M 2205/3306 (2013.01); A61M 2205/52 (2013.01); A61M 2230/432 (2013.01); A61M 2240/00 (2013.01); G09B 23/303 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A computing device-implemented method to determine oxygen consumption in a mechanically ventilated patient, the method comprising:
receiving a signal representing a total flow at an inspiratory outlet of a ventilator;
calculating a transport delay time between inspiratory and expiratory gas sample points in a patient ventilation circuitry;
transmitting a signal to an inlet selector valve to selectively open a fluid path between the inspiratory gas sample point and an oxygen sensor or between the expiratory gas sample point and the oxygen sensor, wherein
the inspiratory gas sample point is located in the fluid path of the patient ventilation system between the patient and a source of air and oxygen, and
the expiratory gas sample point is located in the fluid path of the patient ventilation system between the patient and a fluid outlet or a mixing chamber fluidly connected to the fluid outlet;
receiving data representing oxygen content and carbon dioxide content over a period of time;
calculating oxygen consumption data over the period of time from the data representing the total flow, oxygen content and carbon dioxide content and from the transport delay time; and
displaying the oxygen consumption data over the period of time.