US 11,970,815 B2
Silk protein bonded layered materials and methods of making and using thereof
Gregory H. Altman, Providence, RI (US); Carlos J. Bosques, Arlington, MA (US); and Enrico Mortarino, Hickory, NC (US)
Assigned to EVOLVED BY NATURE, INC., Medford, MA (US)
Appl. No. 17/628,471
Filed by EVOLVED BY NATURE, INC., Medford, MA (US)
PCT Filed Jul. 18, 2020, PCT No. PCT/US2020/042690
§ 371(c)(1), (2) Date Jan. 19, 2022,
PCT Pub. No. WO2021/016139, PCT Pub. Date Jan. 28, 2021.
Claims priority of provisional application 62/903,657, filed on Sep. 20, 2019.
Claims priority of provisional application 62/876,386, filed on Jul. 19, 2019.
Prior Publication US 2022/0275573 A1, Sep. 1, 2022
Int. Cl. D06N 3/14 (2006.01); D06N 3/12 (2006.01)
CPC D06N 3/126 (2013.01) [D06N 3/128 (2013.01); D06N 3/14 (2013.01); D06N 2201/042 (2013.01); D06N 2201/06 (2013.01); D06N 2211/28 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A single or multilayered material comprising a plurality of fibers, filaments, powders, particles, or yarns, and a silk derived protein,
wherein the silk derived protein comprises silk fibroin proteins or fragments thereof having an average weight average molecular weight selected from between about 1 kDa and about 5 kDa, between about 5 kDa and about 10 kDa, between about 6 kDa and about 17 kDa, between about 10 kDa and about 15 kDa, between about 15 kDa and about 20 kDa, between about 17 kDa and about 39 kDa, between about 20 kDa and about 25 kDa, between about 25 kDa and about 30 kDa, between about 30 kDa and about 35 kDa, between about 35 kDa and about 40 kDa, between about 39 kDa and about 80 kDa, between about 40 kDa and about 45 kDa, between about 45 kDa and about 50 kDa, between about 60 kDa and about 100 kDa, and between about 80 kDa, and a polydispersity between 1 and about 5.