US 12,288,601 B2
Flow cytometer, data transmission method, and information processing system
Hiroo Tatsutani, Kobe (JP); Tomohiro Tsuji, Kobe (JP); and Hajimu Kawakami, Kobe (JP)
Assigned to SYSMEX CORPORATION, Kobe (JP)
Filed by SYSMEX CORPORATION, Kobe (JP)
Filed on Sep. 24, 2019, as Appl. No. 16/579,952.
Claims priority of application No. 2018-179994 (JP), filed on Sep. 26, 2018.
Prior Publication US 2020/0098452 A1, Mar. 26, 2020
Int. Cl. G16H 10/20 (2018.01); G01N 15/1429 (2024.01); G16H 10/40 (2018.01); G16H 10/60 (2018.01)
CPC G16H 10/20 (2018.01) [G01N 15/1429 (2013.01); G16H 10/40 (2018.01); G16H 10/60 (2018.01)] 17 Claims
OG exemplary drawing
 
1. A flow cytometer for measuring particles in a sample treated with plural kinds of labeling antibody pigments to acquire particle data comprising plural kinds of optical information of the particles, respective ones of the plural kinds of optical information being attributable to respective ones of the plural kinds of labeling antibody pigments, the flow cytometer comprising:
a flow cell,
light sources configured to emit light to the particles in the sample passing through the flow cell;
light receiving elements including first and second light receiving elements, the first light receiving element receiving first fluorescence from the particles in the sample that are labeled with a first fluorescent labeling antibody pigment and the second light receiving element receiving second fluorescence from the particles in the sample that are labeled with a second fluorescent labeling antibody pigment;
a processor configured with a program to perform operations comprising:
receiving order information comprising a measurement item and a measurement condition associated with the measurement item, the measurement condition of the measurement item comprising: (1) adjustment information on adjustment of detection sensitivity for detecting the plural kinds of optical information; (2) correction information on correction of the plural kinds of optical information to extract the first fluorescence from a first detection signal detected by the first light receiving element and to extract the second fluorescence from a second detection signal detected by the second light receiving element; and (3) gating information comprising a selection of one or more distribution regions in accordance with the measurement item in each of one or more particle distribution diagrams;
measuring according to the measurement condition of the measurement item, the particles in the sample treated with the plural kinds of labeling antibody pigments to acquire particle data comprising the plural kinds of optical information of the particles, the measuring comprising:
adjusting the detection sensitivity based on the adjustment information;
extracting the first fluorescence from the first detection signal detected by the first light receiving element and extracting the second fluorescence from the second detection signal detected by the second light receiving element based on the correction information; and selecting one or more distribution regions in accordance with the measurement item in each of one or more particle distribution diagrams based on the gating information;
generating at least one of: particle distribution diagram output information comprising one or more dot plots of the particles based on the particle data; and image data representing one or more dot plots of the particles based on the particle data; and
transmitting at least one of the particle data, the particle distribution diagram output information, and the image data, to at least one of a hospital information system that supports hospital operations and a clinical laboratory information system that supports clinical test operations.