	US 12,286,459 B2
	Insecticidal toxin receptors and methods of use
Claire Marie Bazyk, Fremont, CA (US); Catherine J Clark, Altoona, IA (US); Ruth Cong, Palo Alto, CA (US); James M Hasler, Danville, IN (US); Jingtong Hou, San Pablo, CA (US); Naga Kishore Kakani, Fremont, CA (US); Deirdre Kapka-Kitzman, Ankeny, IA (US); Song Leng, Castro Valley, CA (US); John P Mathis, Johnston, IA (US); Mark Edward Nelson, Waukee, IA (US); and Takashi Yamamoto, Dublin, CA (US)
Assigned to PIONEER HI-BRED INTERNATIONAL, INC., Johnston, IA (US)
Appl. No. 17/266,318
Filed by PIONEER HI-BRED INTERNATIONAL, INC., Johnston, IA (US)
PCT Filed Aug. 2, 2019, PCT No. PCT/US2019/044771 § 371(c)(1), (2) Date Feb. 5, 2021, PCT Pub. No. WO2020/036747, PCT Pub. Date Feb. 20, 2020.
Claims priority of provisional application 62/718,232, filed on Aug. 13, 2018.
Prior Publication US 2022/0380418 A1, Dec. 1, 2022
Int. Cl. C07K 14/435 (2006.01); C07K 16/28 (2006.01); C12N 15/90 (2006.01); C12Q 1/6888 (2018.01); G01N 33/68 (2006.01)

CPC C07K 14/43563 (2013.01) [C07K 16/28 (2013.01); C12N 15/902 (2013.01); C12Q 1/6888 (2013.01); G01N 33/68 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/43552 (2013.01)]

1 Claim

1. A method for identifying compounds that bind to a polypeptide comprising an amino acid sequence having at least 90% sequence identity to the amino acid sequence set forth in SEQ ID NO: 197, said method comprising:

a. contacting the polypeptide with one or more test compounds; and

b. determining whether the test compound binds to the polypeptide.