| CPC B01L 3/502715 (2013.01) [G01N 35/1004 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/087 (2013.01); B01L 2200/141 (2013.01); B01L 2300/046 (2013.01); B01L 2300/0609 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/049 (2013.01)] | 5 Claims |
|
1. A microfluidic system comprising:
a chip holder that holds a microchip, the microchip including at least one flow channel including a separation flow channel for separating a sample inside and a plurality of reservoirs that open at ends of the at least one flow channel;
a chip cover arranged as being opposed to the microchip held by the chip holder and provided with a plurality of probe insertion portions at positions corresponding to the plurality of reservoirs;
a plurality of sealing members that seal gaps between the plurality of probe insertion portions and the plurality of reservoirs such that the plurality of probe insertion portions can communicate with the plurality of reservoirs;
a dispensing probe provided to introduce a liquid into any of the plurality of reservoirs;
a suction mechanism including a plurality of suction nozzles provided to suction the liquid from the plurality of reservoirs;
a first storage where a first cleaning solution for cleaning the at least one flow channel is stored;
a second storage where a second cleaning solution for cleaning the at least one flow channel is stored;
a pump provided to repeat suction of the liquid and discharge of the liquid;
a channel switch configured to switch between a channel through which the first cleaning solution is suctioned from the first storage and a channel through which the second cleaning solution is suctioned from the second storage; and
a controller that at least controls operations of the channel switch and the pump, wherein
the channel switch includes a first port connected to the dispensing probe through a first channel, a second port connected through a second channel to a downstream side of the pump in a direction of discharge in discharging the liquid from the pump, a third port connected through a third channel to an upstream side of the pump in the direction of discharge, and a fourth port connected to the first storage through a fourth channel,
the channel switch is configured to take at least any of a first state and a second state, the first state being a state that the first port and the second port are connected to each other and the downstream side of the pump and the dispensing probe communicate with each other, the second state being a state that the third port and the fourth port are connected to each other and the upstream side of the pump and the first storage communicate with each other,
the controller controls the operations of the channel switch and the pump such that, in cleaning the at least one flow channel, after the pump suctions the first cleaning solution from the first storage in the second state, the first state is set and the first cleaning solution is introduced from the dispensing probe to any of the plurality of reservoirs,
the controller controls the operations of the channel switch and the pump such that, after introduction of the first cleaning solution, the second cleaning solution is suctioned from the second storage and the second cleaning solution is introduced from the dispensing probe into any of the plurality of reservoirs, and
the third port is connected through a third channel directly to an upstream side of the pump in the direction of discharge.
|