| CPC A61M 5/16831 (2013.01) [A61B 5/14532 (2013.01); A61B 5/4839 (2013.01); A61B 5/7275 (2013.01); A61M 5/1723 (2013.01); G16H 20/17 (2018.01); A61M 2205/18 (2013.01)] | 20 Claims |

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1. A method for insulin therapy, the method comprising:
identifying an amount of future insulin deliveries to be delivered by an infusion device;
determining a homeostasis metric by predicting a change in a current glucose measurement value based on accounting for metabolism of a current amount of active insulin and the amount of future insulin deliveries; and
generating an alert based at least in part on the homeostasis metric.
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