US 12,285,567 B2
High flow oxygen therapy with on-demand humidification and an active exhalation valve
Robert Romano, Pittsburgh, PA (US)
Assigned to KONINKLIJKE PHILIPS N.V., Eindhoven (NL)
Appl. No. 16/468,428
Filed by KONINKLIJKE PHILIPS N.V., Eindhoven (NL)
PCT Filed Dec. 13, 2017, PCT No. PCT/EP2017/082621
§ 371(c)(1), (2) Date Jun. 11, 2019,
PCT Pub. No. WO2018/109006, PCT Pub. Date Jun. 21, 2018.
Claims priority of provisional application 62/433,872, filed on Dec. 14, 2016.
Prior Publication US 2021/0213234 A1, Jul. 15, 2021
Int. Cl. A61M 16/10 (2006.01); A61M 16/20 (2006.01)
CPC A61M 16/101 (2014.02) [A61M 16/205 (2014.02); A61M 2016/102 (2013.01)] 10 Claims
OG exemplary drawing
 
1. A system for delivering a humidified flow of concentrated oxygen containing gas to a subject having a mouth and nares, the system comprising:
a subject interface structured to engage the mouth and/or nares of the subject;
an oxygen concentrator operatively coupled to the subject interface via a first control valve and a first conduit, the oxygen concentrator configured to provide a flow of concentrated oxygen containing gas to the subject interface via the first conduit;
a flow generator operatively coupled to the first conduit between the first control valve and the subject interface via a second control valve;
an aerosol generator operatively coupled to a water supply via a second conduit, the aerosol generator configured to provide a water vapor to the subject interface to humidify the flow of concentrated oxygen containing gas at the subject interface;
an exhalation valve operatively coupled to the subject interface, the exhalation valve configured to control an expiratory pressure of gas expired by the subject;
one or more sensors configured to generate output signals that convey information related to one or more parameters of the concentrated oxygen containing gas; and
a controller configured to:
activate the aerosol generator responsive to the one or more parameters indicating a start of an inspiration, and de-activate the aerosol generator responsive to the one or more parameters indicating a start of an expiration;
control operations of the exhalation valve such that the exhalation valve is opened responsive to the one or more parameters indicating a start of an expiration, and the exhalation valve is closed responsive to the one or more parameters indicating a start of an inspiration; and
control operations of the first control valve to provide a controlled pressure and/or flow of breathable gas to the subject.