	US 12,285,499 B2
	Tissue stain and use thereof
Mary Jo Timm, Littleton, MA (US); Robert G. Whalen, Willington, CT (US); Amy A. Cameron, Union, CT (US); and Patrick Lee, Long Grove, IL (US)
Assigned to GI SUPPLY, Mechanicsburg, PA (US)
Filed by GI SUPPLY, Mechanicsburg, PA (US)
Filed on Sep. 12, 2022, as Appl. No. 17/942,390.
Application 17/942,390 is a continuation of application No. 15/690,178, filed on Aug. 29, 2017, granted, now 11,452,783.
Prior Publication US 2023/0001022 A1, Jan. 5, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 49/00 (2006.01); A61B 90/00 (2016.01)

CPC A61K 49/006 (2013.01) [A61K 49/0093 (2013.01); A61B 90/39 (2016.02); A61B 2090/395 (2016.02)]

25 Claims

1. A liquid tissue staining composition comprising:

deagglomerated carbon particles at a concentration of from about 0.025% to 2.0% (w/v) having a mean particle diameter of from about 0.05 μm to less than 0.2 μm;

an anti-settling agent; (ASA) at a concentration of from about 0.1% to about 1.0% (w/v), and wherein the ASA is selected from the group of hydroxyethyl cellulose, hydroxypropyl cellulose, dextran, and guar gum; and

an optional mucoadhesive agent.