US 12,285,470 B2
Trim proteins and galectins cooperate and codirect autophagy and are useful in the treatment of autophagy related diseases
Vojo Deretic, Placitas, NM (US)
Assigned to UNM RAINFOREST INNOVATIONS, Albuquerque, NM (US)
Appl. No. 16/321,699
Filed by UNM RAINFOREST INNOVATIONS, Albuquerque, NM (US)
PCT Filed Jul. 31, 2017, PCT No. PCT/US2017/044619
§ 371(c)(1), (2) Date Jan. 29, 2019,
PCT Pub. No. WO2018/023108, PCT Pub. Date Feb. 1, 2018.
Claims priority of provisional application 62/368,624, filed on Jul. 29, 2016.
Prior Publication US 2024/0261378 A1, Aug. 8, 2024
Int. Cl. A61K 38/53 (2006.01); A61K 31/05 (2006.01); A61K 31/137 (2006.01); A61K 31/155 (2006.01); A61K 31/436 (2006.01); A61K 31/4375 (2006.01); A61K 31/616 (2006.01); A61K 31/7016 (2006.01); A61K 31/702 (2006.01); A61K 38/17 (2006.01); A61K 45/06 (2006.01); A61P 31/04 (2006.01)
CPC A61K 38/53 (2013.01) [A61K 31/05 (2013.01); A61K 31/137 (2013.01); A61K 31/155 (2013.01); A61K 31/436 (2013.01); A61K 31/4375 (2013.01); A61K 31/616 (2013.01); A61K 31/7016 (2013.01); A61K 31/702 (2013.01); A61K 38/1732 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01)] 20 Claims
OG exemplary drawing
 
1. A method of treating a Mycobacterium tuberculosis infection in a patient or subject in need comprising administering to said patient or subject an effective amount of TRIM 16 protein and at least one galectin selected from the group consisting of galectin 3, galectin 8 and galectin 9.