US 12,285,396 B2
Co-crystal of ketoprofen, compositions comprising the same, process of producing the same, and uses thereof
Andrea Aramini, L'Aquila (IT); Gianluca Bianchini, L'Aquila (IT); and Samuele Lillini, Cardito (IT)
Assigned to DOMPÉ FARMACEUTICI S.P.A., Milan (IT)
Appl. No. 17/416,627
Filed by DOMPÉ FARMACEUTICI S.P.A., Milan (IT)
PCT Filed Dec. 20, 2019, PCT No. PCT/EP2019/025464
§ 371(c)(1), (2) Date Jun. 21, 2021,
PCT Pub. No. WO2020/126088, PCT Pub. Date Jun. 25, 2020.
Claims priority of application No. 18215336 (EP), filed on Dec. 21, 2018.
Prior Publication US 2022/0071936 A1, Mar. 10, 2022
Int. Cl. A61K 31/192 (2006.01); A61K 47/54 (2017.01)
CPC A61K 31/192 (2013.01) [A61K 47/542 (2017.08)] 14 Claims
 
1. A co-crystal of Ketoprofen Lysine Form 1 characterized by having an X-ray diffraction pattern with characteristic peaks at 16.3; 17.5; 17.6; 17.7; 19.6; 19.7° 2theta±0.20 degrees.