US 12,285,271 B2
Continuous analyte monitoring system with microneedle array
Alan Campbell, San Diego, CA (US); Sirilak Sattayasamitsathit, San Diego, CA (US); Jared Rylan Tangney, Encinitas, CA (US); Joshua Ray Windmiller, San Diego, CA (US); and James Patrick McCanna, San Diego, CA (US)
Assigned to Biolinq Incorporated, San Diego, CA (US)
Filed by Biolinq Incorporated, San Diego, CA (US)
Filed on Oct. 24, 2024, as Appl. No. 18/926,029.
Application 18/926,029 is a continuation of application No. 18/630,936, filed on Apr. 9, 2024.
Application 18/630,936 is a continuation of application No. 18/086,543, filed on Dec. 21, 2022, granted, now 12,011,294, issued on Jun. 18, 2024.
Application 18/086,543 is a continuation of application No. PCT/US2021/043786, filed on Jul. 29, 2021.
Claims priority of provisional application 63/058,275, filed on Jul. 29, 2020.
Prior Publication US 2025/0049397 A1, Feb. 13, 2025
Int. Cl. A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61B 5/1486 (2006.01); G01N 27/327 (2006.01)
CPC A61B 5/685 (2013.01) [A61B 5/0022 (2013.01); A61B 5/14514 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/14865 (2013.01); A61B 5/6833 (2013.01); A61B 5/742 (2013.01); G01N 27/327 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A microneedle array for use in sensing an analyte, comprising:
a semiconductor substrate; and
a plurality of microneedles formed from the semiconductor substrate, the plurality of microneedles comprising:
a first microneedle comprising a first working electrode comprising a first biorecognition element configured to react with the analyte;
a second microneedle comprising a second working electrode comprising a second biorecognition element configured to react with the analyte; and
a third microneedle comprising a counter electrode,
wherein each of the first microneedle, the second microneedle, and the third microneedle are insulated from the semiconductor substrate and electrically isolated from one another such that a first redox reaction between the first working electrode and the counter electrode and a second redox reaction between the second working electrode and the counter electrode are independent of one another.