US 12,285,263 B2
Assessing neural state from action potentials
John Louis Parker, Artarmon (AU)
Assigned to Saluda Medical Pty Ltd, Macquarie Park (AU)
Filed by Saluda Medical Pty Ltd, Artarmon (AU)
Filed on May 31, 2022, as Appl. No. 17/804,846.
Application 17/804,846 is a continuation of application No. 15/129,407, abandoned, previously published as PCT/AU2015/050135, filed on Mar. 27, 2015.
Claims priority of application No. 2014901110 (AU), filed on Mar. 28, 2014.
Prior Publication US 2022/0287620 A1, Sep. 15, 2022
Int. Cl. A61B 5/00 (2006.01); A61B 5/24 (2021.01); A61B 5/388 (2021.01); A61N 1/36 (2006.01)
CPC A61B 5/4076 (2013.01) [A61B 5/388 (2021.01); A61B 5/4041 (2013.01); A61B 5/407 (2013.01); A61B 5/4824 (2013.01); A61B 5/4836 (2013.01); A61N 1/36071 (2013.01); A61N 1/36135 (2013.01); A61N 1/36185 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method of assessing a neural state of a subject, the method comprising:
obtaining a recording of a compound action potential arising in neural tissue of the subject from one or more implanted sense electrodes of an implantable neurostimulator;
providing to a processor of a control device the recording of the compound action potential;
processing, by the processor, the recording to detect an anomaly in a profile of the recorded compound action potential by determining whether a peak in the recorded compound action potential has an atypically swift rate of rise;
generating, by the processor, an indication regarding the neural state of the subject based on detected anomalies in the recorded compound action potential;
outputting, by the processor, the indication regarding the neural state of the subject; and
configuring, by the processor, the implantable neurostimulator using the indication regarding the neural state of the subject.