US 12,285,010 B2
Sample cooling and storage mechanism
Jianguo Qu, Shanghai (CN); and Zhikang Liu, Shanghai (CN)
Assigned to SHANGHAI ORIGINCELL BIOLOGICAL CRYO EQUIPMENT CO., LTD., Shanghai (CN)
Appl. No. 18/286,588
Filed by SHANGHAI ORIGINCELL BIOLOGICAL CRYO EQUIPMENT CO., LTD., Shanghai (CN)
PCT Filed Mar. 25, 2022, PCT No. PCT/CN2022/082896
§ 371(c)(1), (2) Date Oct. 12, 2023,
PCT Pub. No. WO2022/237344, PCT Pub. Date Nov. 17, 2022.
Claims priority of application No. 202120995343.1 (CN), filed on May 11, 2021.
Prior Publication US 2024/0196884 A1, Jun. 20, 2024
Int. Cl. F25D 16/00 (2006.01); A01N 1/145 (2025.01); A01N 1/162 (2025.01)
CPC A01N 1/145 (2025.01) [A01N 1/162 (2025.01)] 17 Claims
OG exemplary drawing
 
1. A sample cooling and storage mechanism, comprising:
a refrigeration device and a gradient cooling device;
wherein the refrigeration device is configured to perform temperature-controlled refrigeration on storage vials;
the gradient cooling device is configured to perform programmed gradient cooling on the storage vials;
the refrigeration device comprises at least one refrigeration zone; a nitrogen spraying component, a heating component and a storage vial rack are provided in the refrigeration zone; the nitrogen spraying component is configured to spray nitrogen in the refrigeration zone; and the heating component heats an interior of the refrigeration zone;
the refrigeration device comprises a plurality of refrigeration zones, and the plurality of refrigeration zones are arranged in an array in a refrigerator component;
an upper end of the refrigeration device is provided with a movable insulation cover, and the movable insulation cover rolls or slides to open or close the refrigeration device;
the movable insulation cover comprises two parallel guide rails, a movable rod with two ends slidably provided on the guide rails, and a flexible insulation cover with one end provided on the movable rod and the other end connected to a counterweight and suspended; and
the movable insulation cover further comprises a drive motor and a drive shaft connected to an output shaft of the drive motor; a driving wheel is provided on the drive shaft; the driving wheel is synchronized and connected to a driven wheel through a driving belt; a second slider is provided on the driving belt; an end of the movable rod is fixedly connected to the second slider; and the second slider is slidably fit with the guide rail.
 
6. A sample cooling and storage mechanism, comprising:
a refrigeration device and a gradient cooling device;
wherein the refrigeration device is configured to perform temperature-controlled refrigeration on storage vials;
the gradient cooling device is configured to perform programmed gradient cooling on the storage vials;
the refrigeration device comprises at least one refrigeration zone; a nitrogen spraying component, a heating component and a storage vial rack are provided in the refrigeration zone; the nitrogen spraying component is configured to spray nitrogen in the refrigeration zone; and the heating component heats an interior of the refrigeration zone;
the gradient cooling device comprises a liquid-nitrogen container, a storage rack located above an opening of the liquid-nitrogen container, and a storage rack lifting device for driving the storage rack to move up and down; and
the storage rack lifting device comprises a frame and a lifter fixed to the frame; a lifting platform of the lifter is provided with a mounting plate; the storage rack is provided at a bottom end of the mounting plate; a lifting motor is provided on the mounting plate; a body of the lifting motor is fixed to the mounting plate; an output shaft of the lifting motor is connected to a screw rod; the screw rod is threaded to a first slider; and the first slider is slidably fit with the mounting plate, and a temperature sensor is provided on the first slider.