US 12,283,459 B2
Nanofluidic cell and loading platform
Germán Sciaini, Waterloo (CA); and Ariel Petruk, Waterloo (CA)
Appl. No. 17/428,876
Filed by Germán Sciaini, Waterloo (CA); and Ariel Petruk, Waterloo (CA)
PCT Filed Feb. 5, 2020, PCT No. PCT/CA2020/050144
§ 371(c)(1), (2) Date Aug. 5, 2021,
PCT Pub. No. WO2020/160661, PCT Pub. Date Aug. 13, 2020.
Claims priority of provisional application 62/801,327, filed on Feb. 5, 2019.
Prior Publication US 2022/0102110 A1, Mar. 31, 2022
Int. Cl. H01J 37/16 (2006.01); H01J 37/20 (2006.01); H01J 37/22 (2006.01); H01J 37/26 (2006.01)
CPC H01J 37/261 (2013.01) [H01J 37/16 (2013.01); H01J 37/20 (2013.01); H01J 37/226 (2013.01)] 18 Claims
OG exemplary drawing
 
1. Apparatus for use with an electron microscope and for receiving a liquid sample droplet, the apparatus comprising:
a pair of parts which, in use, are disposed in abutting relation to one another to define a cell for use with said microscope, the cell having: disposed on opposite surfaces thereof, a pair of windows, the windows being arranged in spaced relation to one another to define a viewable interior volume of the cell at the region of overlap; and a cavity communicating with the viewable interior volume of the cell, the cavity, in combination with the viewable interior volume, being larger than the volume of the droplet and sealed
wherein
each part of the pair is defined, at least in part, by a respective body, each body defining a respective one of the windows;
one of the bodies defines a surface in which the window of such body is defined; and
the surface is one or more of the end of a boss and a surface having a high affinity for the liquid sample droplet.