| CPC G06T 7/33 (2017.01) [G06T 7/0012 (2013.01); G06T 2207/10081 (2013.01); G06T 2207/10088 (2013.01); G06T 2207/10104 (2013.01)] | 20 Claims |

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1. A gantry alignment system, comprising:
a non-radioactive structure positioned in a field-of-view of a multimodality medical scanner;
a non-transitory memory device for storing computer readable program code; and
a processor device in communication with the non-transitory memory device, the processor device being operative with the computer readable program code to perform steps including
acquiring first image data of the non-radioactive structure by using intrinsic radiation emitted by scintillator crystals of detectors of a first modality in the multimodality medical scanner,
acquiring second image data of the non-radioactive structure by using a second modality of the multimodality medical scanner,
performing image reconstruction based on the first and second image data of the non-radioactive structure to generate first and second reconstructed image volumes, and
determining a gantry alignment transformation based on the first and second image data by aligning the first and second reconstructed image volumes.
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