	US 12,281,317 B2
	Non-human organism for producing triacylglycerol
Peter Eastmond, Harpenden (GB); Henricus Egbertus Gerardus Van Erp, Harpenden (GB); and Govindprasad Bhutada, Harpenden (GB)
Assigned to ROTHAMSTED RESEARCH LTD, Harpenden (GB)
Appl. No. 17/633,390
Filed by ROTHAMSTED RESEARCH LTD, Harpenden (GB)
PCT Filed Aug. 6, 2020, PCT No. PCT/GB2020/051875 § 371(c)(1), (2) Date Feb. 7, 2022, PCT Pub. No. WO2021/023991, PCT Pub. Date Feb. 11, 2021.
Claims priority of application No. 1911317 (GB), filed on Aug. 7, 2019.
Prior Publication US 2022/0282267 A1, Sep. 8, 2022
Int. Cl. C12N 1/20 (2006.01); A23L 33/115 (2016.01); C12N 15/82 (2006.01)

CPC C12N 15/8247 (2013.01) [A23L 33/115 (2016.08)]

23 Claims

1. A plant or fungal organism for producing triacylglycerol

(A) wherein the plant or fungal organism is genetically modified to express a lysophosphatidic acid acyltransferase specific for C16:0-Coenzyme A (C16:0 LPAT) and wherein, once expressed, the C16:0 LPAT is localised in the endoplasmic reticulum; or

(B) in which:

(a) a lysophosphatidic acid acyltransferase specific for C16:0-Coenzyme A (C16:0 LPAT) is localised in the endoplasmic reticulum; and

(b) activity of native endoplasmic reticulum lysophosphatidic acid acyltransferase (ER LPAT) is suppressed or prevented.