	US 12,281,311 B1
	Composition for regulating production of interfering ribonucleic acid
Bradley G. Thompson, Calgary (CA)
Assigned to Wyvern Pharmaceuticals Inc., Calgary (CA)
Filed by Wyvern Pharmaceuticals Inc., Calgary (CA)
Filed on Feb. 20, 2024, as Appl. No. 18/582,279.
Int. Cl. C12N 15/11 (2006.01); C12N 15/113 (2010.01)

CPC C12N 15/1138 (2013.01) [C12N 2310/141 (2013.01)]

9 Claims

1. A composition that comprises a recombinant plasmid (RP) that comprises a sequence of nucleotides that encodes for a sequence of micro-interfering ribonucleic acid (miRNA) that binds to and degrades messenger ribonucleic acid (mRNA) that encodes for an opioid receptor, wherein the sequence of nucleotides is 95-100% the same as one of SEQ ID NO. 2, SEQ ID NO. 3, SEQ ID NO. 4 or SEQ ID NO. 5.