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1. A method of inhibiting the growth of a cancer cell or killing a cancer cell, the method comprising introducing into the cancer cell a double-stranded RNA comprising a passenger strand and a guide strand that form a duplex having a length of 15-30 nucleotides, wherein: (i) the passenger strand comprises a trinucleotide repeat sequence (CAG)n, wherein n is an integer from 3-10; (ii) the guide strand comprises a trinucleotide repeat sequence (CUG)n, wherein n is an integer from 3-10; and (iii) the (CUG)n and (CAG)n trinucleotide repeat sequences hybridize to each other to form at least part of the duplex, and (iv) the passenger strand comprises one or more modified nucleotides at the 5′-terminus that prevents loading of the passenger strand into an RNA-induced silencing complex (RISC), wherein the cancer cell is derived from an adenocarcinoma, leukemia, lymphoma, melanoma, myeloma, sarcoma, or teratocarcinoma or is derived from a cell of the adrenal gland, bladder, bone, bone marrow, brain, cervix, gall bladder, ganglia, gastrointestinal tract, heart, kidney, liver, lung, muscle, ovary, pancreas, parathyroid, skin, testis, thymus, or uterus.
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