US 12,281,117 B2
Small molecule immune agonists and immune targeting compounds and application thereof
Guangyi Jin, Guangdong (CN); Zhulin Wang, Guangdong (CN); and Li Tang, Guangdong (CN)
Assigned to SHENZHEN UNIVERSITY, Shenzhen (CN)
Appl. No. 17/044,659
Filed by SHENZHEN UNIVERSITY, Guangdong (CN)
PCT Filed Apr. 2, 2019, PCT No. PCT/CN2019/080945
§ 371(c)(1), (2) Date Mar. 17, 2021,
PCT Pub. No. WO2019/192454, PCT Pub. Date Oct. 10, 2019.
Claims priority of application No. 201810289351.7 (CN), filed on Apr. 3, 2018; and application No. 201810331582.X (CN), filed on Apr. 13, 2018.
Prior Publication US 2021/0038605 A1, Feb. 11, 2021
Prior Publication US 2023/0148436 A2, May 11, 2023
Int. Cl. A61K 31/52 (2006.01); A61K 47/54 (2017.01); A61K 47/64 (2017.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); C07D 473/18 (2006.01)
CPC C07D 473/18 (2013.01) [A61K 31/52 (2013.01); A61K 47/54 (2017.08); A61K 47/545 (2017.08); A61K 47/64 (2017.08); A61K 47/6803 (2017.08); A61P 35/00 (2018.01)] 3 Claims
OG exemplary drawing
 
1. A small-molecule immune agonist that is a SZU-series compound selected from the group consisting of:

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or a pharmaceutically acceptable salt thereof.