US 12,281,060 B2
Remodilins for airway remodeling and organ fibrosis
Julian Solway, Glencoe, IL (US); Nickolai Dulin, Chicago, IL (US); Diane Luci, Germantown, MD (US); David Maloney, Point of Rocks, MD (US); Chan Young Park, Belmont, MA (US); Jeffrey Fredberg, Newton, MA (US); David McCormick, Chicago, IL (US); and Ramaswamy Krishnan, Boston, MA (US)
Assigned to The University of Chicago, Chicago, IL (US); The United States of America, as Represented by the Secretary, Department of Health and Human Services, Bethesda, MD (US); President and Fellows of Harvard College, Cambridge, MA (US); IIT Research Institute, Chicago, IL (US); and Beth Israel Deaconess Medical Center Inc., Boston, MA (US)
Appl. No. 17/594,086
Filed by The University of Chicago, Chicago, IL (US); The United States of America, as Represented by the Secretary, Department of Health and Human Services, Bethesda, MD (US); President and Fellows of Harvard College, Cambridge, MA (US); IIT Research Institute, Chicago, IL (US); Beth Israel Deaconess Medical Center, Inc., Boston, MA (US); REGENTS OF THE UNIVERSITY OF MINNESOTA, Minneapolis, MN (US); and THE TRUSTEES OF PURDUE UNIVERSITY, Lafayette, IN (US)
PCT Filed Apr. 2, 2020, PCT No. PCT/US2020/026371
§ 371(c)(1), (2) Date Oct. 1, 2021,
PCT Pub. No. WO2020/206109, PCT Pub. Date Oct. 8, 2020.
Claims priority of provisional application 62/827,980, filed on Apr. 2, 2019.
Prior Publication US 2022/0177422 A1, Jun. 9, 2022
Int. Cl. C07D 311/46 (2006.01); A61P 11/00 (2006.01); C07C 311/46 (2006.01); C07D 207/48 (2006.01); C07D 211/96 (2006.01); C07D 277/52 (2006.01); C07D 295/26 (2006.01)
CPC C07C 311/46 (2013.01) [A61P 11/00 (2018.01); C07D 207/48 (2013.01); C07D 211/96 (2013.01); C07D 277/52 (2013.01); C07D 295/26 (2013.01); C07C 2601/16 (2017.05)] 3 Claims
 
1. A composition comprising a compound of

OG Complex Work Unit Chemistry
or a salt, enantiomer, or diastereomer thereof.