US 12,280,398 B2
Actuation of microchannels for optimized acoustophoresis
Jason Fiering, Boston, MA (US); and Rebecca Christianson, Southborough, MA (US)
Assigned to The Charles Stark Draper Laboratory, Inc.
Filed by The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US)
Filed on Mar. 5, 2021, as Appl. No. 17/193,485.
Prior Publication US 2022/0280973 A1, Sep. 8, 2022
Int. Cl. B06B 1/06 (2006.01); B81B 1/00 (2006.01)
CPC B06B 1/06 (2013.01) [B81B 1/00 (2013.01); B81B 2201/032 (2013.01); B81B 2201/058 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An actuation plate for acoustophoresis devices, comprising:
a first surface configured to be coupled to an acoustic transducer; and
a second surface, opposite the first surface, coupled to a plurality of microfluidic channels; and
one or more slots defining one or more openings through the actuation plate, the one or more openings extending perpendicular to the plurality of microfluidic channels,
wherein the actuation plate has a thickness selected such that the acoustic transducer generates a standing wave in the actuation plate that concurrently focuses target particles to flow within fluid along a center of each of the plurality of microfluidic channels, and
wherein the actuation plate is constructed from a material having a first elastic modulus and the plurality of microfluidic channels are each constructed from a second material having a second elastic modulus, different from the first elastic modulus.