US 12,280,375 B2
Acoustophoresis devices having conductive electrodes and methods
Jeffrey Jasperse, Newton, MA (US); Peter Paulicka, Forchheim (DE); Michael Palombo, South Boston, MA (US); Ramona Seliger, Wiesenttal-Muggendorf (DE); and Paul Benson, Quincy, MA (US)
Assigned to Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US)
Appl. No. 18/705,197
Filed by Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US)
PCT Filed Oct. 10, 2022, PCT No. PCT/US2022/077832
§ 371(c)(1), (2) Date Apr. 26, 2024,
PCT Pub. No. WO2023/244275, PCT Pub. Date Dec. 21, 2023.
Claims priority of provisional application 63/366,552, filed on Jun. 17, 2022.
Prior Publication US 2024/0416346 A1, Dec. 19, 2024
Int. Cl. B01L 3/00 (2006.01); C12M 1/00 (2006.01)
CPC B01L 3/502761 (2013.01) [B01L 2300/0816 (2013.01); B01L 2400/0436 (2013.01); B01L 2400/0439 (2013.01)] 42 Claims
OG exemplary drawing
 
1. An acoustophoresis device, comprising:
a sample vessel having an outer surface, a microchannel within confines of the outer surface, a first port extending through the outer surface to the microchannel, and a second port extending through the outer surface to the microchannel, the microchannel being configured to receive a blood sample through the first port; the sample vessel having conductive traces on the outer surface; and
a piezo transducer formed on the outer surface of the sample vessel to form a monolithic structure, the piezo transducer contacting at least one of the conductive traces, the piezo transducer configured to generate ultrasonic waves inside the blood sample in the microchannel, the piezo transducer having an excitation input and response signal output electrically connected to the at least one of the conductive traces.