US 12,280,372 B2
Arbitrarily shaped, deep sub-wavelength acoustic manipulation for microparticle and cell patterning
Pei Yu E. Chiou, Oakland, CA (US); Kuan-Wen Tung, Oakland, CA (US); and Benjamin M. Wu, San Marino, CA (US)
Assigned to The Regents of the University of California, Oakland, CA (US)
Appl. No. 17/605,925
Filed by THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US)
PCT Filed Apr. 24, 2020, PCT No. PCT/US2020/029747
§ 371(c)(1), (2) Date Oct. 22, 2021,
PCT Pub. No. WO2020/219831, PCT Pub. Date Oct. 29, 2020.
Claims priority of provisional application 62/837,768, filed on Apr. 24, 2019.
Prior Publication US 2022/0203359 A1, Jun. 30, 2022
Int. Cl. B01L 3/00 (2006.01); B06B 3/00 (2006.01)
CPC B01L 3/50273 (2013.01) [B01L 3/502761 (2013.01); B01L 2300/123 (2013.01); B01L 2300/161 (2013.01); B01L 2300/1894 (2013.01); B01L 2400/0439 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A compliant membrane acoustic patterning device for manipulating particles, comprising:
a piezoelectric layer;
a patterned layer comprising a plurality of cavities disposed on top of the piezoelectric layer, wherein each of the cavities are covered by a membrane that is flush with a top surface of the patterned layer;
a fluid layer disposed on top of the patterned layer;
a plurality of particles immersed in the fluid;
a cover layer disposed on top of the fluid layer; and
an oscillating power source configured to actuate the piezoelectric layer at an oscillation frequency.