US 12,280,323 B2
Systems and methods for removing gaseous micro emboli from blood
Andrea Zaniboni, San Martino Spino (IT); Stefano Spro, Calimera (IT); and Claudio Silvestri, Quarantoli Mirandola (IT)
Assigned to Sorin Group Italia S.r.l., Milan (IT)
Filed by Sorin Group Italia S.r.l., Milan (IT)
Filed on Mar. 7, 2022, as Appl. No. 17/688,184.
Application 17/688,184 is a continuation of application No. PCT/IB2019/058158, filed on Oct. 3, 2019.
Prior Publication US 2022/0184530 A1, Jun. 16, 2022
Int. Cl. B01D 53/22 (2006.01); A61M 1/16 (2006.01); A61M 1/36 (2006.01); B01D 19/00 (2006.01)
CPC B01D 19/0031 (2013.01) [A61M 1/1698 (2013.01); A61M 1/3623 (2022.05); A61M 1/3627 (2013.01); A61M 1/3666 (2013.01); B01D 19/0036 (2013.01); B01D 53/22 (2013.01); A61M 2205/7536 (2013.01)] 13 Claims
OG exemplary drawing
 
9. A system for processing blood to remove gaseous micro emboli from the blood and provide processed blood to an oxygenator that receives oxygenation gases at atmospheric pressure to oxygenate the processed blood, the system comprising:
a module having a blood inlet at one side of the module and configured to receive the blood, a blood outlet at another side of the module and configured to output the processed blood, and a port configured to provide gas at atmospheric or sub-atmospheric pressure; and
microporous hollow fibers situated in the module and open at one or more ends of the microporous hollow fibers to fluidly couple inside passages of the microporous hollow fibers to the port,
wherein the module receives the blood through the blood inlet and the blood flows from the blood inlet to the blood outlet and around outside surfaces of the microporous hollow fibers to draw at least some of the gaseous micro emboli from the blood through the microporous hollow fibers;
wherein the module includes a housing, and the microporous hollow fibers are stacked in layers at least one of horizontally and vertically situated in the housing;
wherein the microporous hollow fibers are stacked in layers with the microporous hollow fibers in each layer crossing the microporous hollow fibers in an adjacent layer at an angle in the housing.