| CPC A61M 25/0026 (2013.01) [A61B 34/20 (2016.02); A61B 90/10 (2016.02); A61M 25/007 (2013.01); A61M 25/10 (2013.01); A61M 39/0208 (2013.01); A61B 2017/00477 (2013.01); A61B 2017/00557 (2013.01); A61B 2017/0225 (2013.01); A61B 2034/2055 (2016.02); A61B 2034/2065 (2016.02); A61M 2039/0232 (2013.01); A61M 2039/0235 (2013.01)] | 41 Claims |

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1. A surgical instrument to enable access to a region of interest within a tissue, the surgical instrument comprising:
a multi-lumen catheter configured to be inserted within the tissue, the multi-lumen catheter comprising:
a first lumen configured to enable a flow of a fluid,
a second lumen configured to receive a navigation probe that facilitates location of the region of interest within the tissue, and
an expandable membrane situated toward a distal end of the first lumen to form an expandable cavity,
wherein the expandable cavity is configured to expand or contract based on the flow of the fluid through the first lumen; and
a fluid line, coupled to the first lumen, that is configured to:
supply the fluid to the first lumen to enable the expandable cavity to expand, and
withdraw the fluid from the first lumen to enable the expandable cavity to contract,
wherein the fluid line is configured to withdraw the fluid from the expandable cavity, into the first lumen, and via the fluid line.
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