US 12,280,148 B2
Composition for promoting extracellular vesicle production containing peptide derived from noxa protein and method for producing extracellular vesicles by using same
Tae-Hyoung Kim, Gwangju (KR); Jung Hee Park, Gwangju (KR); Ji Hye Han, Gwangju (KR); and Seung-Hyun Myung, Gwangju (KR)
Assigned to Exocalibre Therapeutics Co., Ltd., Gwangju (KR)
Appl. No. 17/424,232
Filed by Exocalibre Therapeutics Co., Ltd., Gwangju (KR)
PCT Filed Jun. 3, 2021, PCT No. PCT/KR2021/006905
§ 371(c)(1), (2) Date Jul. 20, 2021,
PCT Pub. No. WO2022/055077, PCT Pub. Date Mar. 17, 2022.
Claims priority of application No. 10-2020-0115145 (KR), filed on Sep. 9, 2020.
Prior Publication US 2022/0304931 A1, Sep. 29, 2022
Int. Cl. A61K 38/08 (2019.01); A61K 9/1277 (2025.01); A61K 31/473 (2006.01); A61K 31/704 (2006.01); A61K 35/13 (2015.01); A61K 38/10 (2006.01); A61K 38/17 (2006.01); A61K 38/19 (2006.01); A61K 45/06 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/47 (2006.01); C12N 5/09 (2010.01); C12N 15/88 (2006.01)
CPC A61K 9/1277 (2013.01) [A61K 31/473 (2013.01); A61K 31/704 (2013.01); A61K 38/177 (2013.01); A61K 48/0033 (2013.01); C12N 5/0693 (2013.01); C12N 15/88 (2013.01); C12N 2501/998 (2013.01); C12N 2510/02 (2013.01)] 5 Claims
 
1. A medium for extracellular vesicle production, the medium comprising: at least one peptide selected from the group consisting of SEQ ID NOs: 2 and 5-15; and a solution containing a sugar.