US 12,280,033 B2
Pharmaceutical combination for the treatment of a cancer
Carles Domènech Garcia, Cerdanyola del Vallès (ES); José Alberto Alfón Coriat, Cerdanyola del Vallès (ES); Héctor Pérez Montoyo, Cerdanyola del Vallès (ES); Miguel Francisco Segura Ginard, Cerdanyola del Vallès (ES); and Jose Miguel Lizcano De Vega, Cerdanyola del Vallès (ES)
Assigned to ABILITY PHARMACEUTICALS S.L., Cerdanyola del Vallès (ES)
Filed by ABILITY PHARMACEUTICALS S.L., Cerdanyola del Vallès (ES)
Filed on Jul. 3, 2024, as Appl. No. 18/763,671.
Application 18/763,671 is a continuation of application No. 17/581,587, filed on Jan. 21, 2022, granted, now 12,053,449.
Application 17/581,587 is a continuation of application No. 16/614,084, granted, now 11,260,042, issued on Mar. 1, 2022, previously published as PCT/EP2018/062554, filed on May 15, 2018.
Claims priority of application No. 17382282 (EP), filed on May 16, 2017.
Prior Publication US 2024/0350449 A1, Oct. 24, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/201 (2006.01); A61K 31/28 (2006.01); A61K 31/282 (2006.01); A61K 31/335 (2006.01); A61K 31/337 (2006.01); A61K 31/517 (2006.01); A61K 31/555 (2006.01); A61K 33/243 (2019.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01)
CPC A61K 31/282 (2013.01) [A61K 31/201 (2013.01); A61K 31/337 (2013.01); A61K 33/243 (2019.01); A61K 45/06 (2013.01); A61P 35/04 (2018.01)] 20 Claims
 
1. A pharmaceutical combination for the treatment of cancer comprising:
(i) a Compound (A) which comprises a polyunsaturated fatty acid of formula COOH—CHOH—(CH2)6—(CH—CH—CH2)2—(CH2)3—CH3 (ABTL0812), a pharmaceutically acceptable salt thereof, or a combination thereof
and
(ii) a Compound (B) which comprises at least one chemotherapeutic agent compound selected from the group consisting of a platinum-based agent, a nucleotide analog or precursor analog, an inhibitor of topoisomerase, or a combination thereof; and,
wherein the cancer is a tumor.