US 12,280,029 B2
Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
Carlos Batthyány, Montevideo (UY); Gloria Virginia López, Montevideo (UY); Carlos Escande, Montevideo (UY); Jorge Rodriguez Duarte, Ciudad de la Costa (UY); Williams Arturo Porcal Quinta, Montevideo (UY); Rosina Dapueto Capuccio, Montevideo (UY); Germán Adrian Galliussi López, Montevideo (UY); Maria Pia Garat Nuñez, Montevideo (UY); Marcelo Hill, Canelones (UY); and Mercedes Segovia, Canelones (UY)
Assigned to INSTITUT PASTEUR DE MONTEVIDEO, Montevideo (UY); and UNIVERSIDAD DE LA REPUBLICA, Montevideo (UY)
Filed by INSTITUT PASTEUR DE MONTEVIDEO, Montevideo (UY); and UNIVERSIDAD DE LA REPÚBLICA, Montevideo (UY)
Filed on Jun. 6, 2022, as Appl. No. 17/833,315.
Application 17/833,315 is a division of application No. 16/746,035, filed on Jan. 17, 2020, granted, now 11,400,066.
Application 16/746,035 is a continuation of application No. 15/784,685, filed on Oct. 16, 2017, granted, now 10,537,537, issued on Jan. 21, 2020.
Claims priority of provisional application 62/570,973, filed on Oct. 11, 2017.
Claims priority of provisional application 62/408,459, filed on Oct. 14, 2016.
Prior Publication US 2022/0296546 A1, Sep. 22, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/192 (2006.01); A61K 45/06 (2006.01)
CPC A61K 31/192 (2013.01) [A61K 45/06 (2013.01)] 19 Claims
 
1. A method of treating organ transplant rejection comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula I:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.