US 12,279,990 B2
Devices, systems, and methods for modulating tissue temperature
Rafael Eduardo Chaparro, Durham, NC (US); Paolo Maccarini, Durham, NC (US); Luis Fernando Gonzalez, Durham, NC (US); Donald Pearce, Durham, NC (US); Edward Lysk Wyckoff, III, Durham, NC (US); Syed Faaiz Enam, Durham, NC (US); Jikai Shen, Durham, NC (US); Aliesha O'Raw, Durham, NC (US); and Rachel Yang, Durham, NC (US)
Assigned to DUKE UNIVERSITY, Durham, NC (US)
Appl. No. 17/273,548
Filed by DUKE UNIVERSITY, Durham, NC (US)
PCT Filed Sep. 6, 2019, PCT No. PCT/US2019/049988
§ 371(c)(1), (2) Date Mar. 4, 2021,
PCT Pub. No. WO2020/051480, PCT Pub. Date Mar. 12, 2020.
Claims priority of provisional application 62/727,617, filed on Sep. 6, 2018.
Prior Publication US 2021/0330490 A1, Oct. 28, 2021
Int. Cl. A61F 7/12 (2006.01); A61F 7/00 (2006.01)
CPC A61F 7/12 (2013.01) [A61F 7/007 (2013.01); A61F 2007/0002 (2013.01); A61F 2007/0056 (2013.01); A61F 2007/0076 (2013.01); A61F 2007/126 (2013.01)] 32 Claims
OG exemplary drawing
 
1. A device for modulating temperature of a tissue in a subject, the device comprising:
a heat exchanger comprising a proximal end and a distal end, wherein the distal end of the heat exchanger comprises a plurality of perforated fins; and
at least one thermoelectric modulator coupled to the proximal end of the heat exchanger.