US 12,279,861 B2
Color changing detection patch utilizing microneedle sampling of interstitial fluid
Robert M Taylor, Albuquerque, NM (US); and Justin T Baca, Albuquerque, NM (US)
Assigned to UNM Rainforest Innovations, Albuquerque, NM (US)
Appl. No. 17/274,866
Filed by UNM Rainforest Innovations, Albuquerque, NM (US)
PCT Filed Sep. 10, 2019, PCT No. PCT/US2019/050302
§ 371(c)(1), (2) Date Mar. 10, 2021,
PCT Pub. No. WO2020/055791, PCT Pub. Date Mar. 19, 2020.
Claims priority of provisional application 62/728,935, filed on Sep. 10, 2018.
Prior Publication US 2022/0047190 A1, Feb. 17, 2022
Int. Cl. A61B 5/145 (2006.01); A61B 5/00 (2006.01); A61B 10/00 (2006.01)
CPC A61B 5/14514 (2013.01) [A61B 5/14546 (2013.01); A61B 5/4833 (2013.01); A61B 5/4845 (2013.01); A61B 5/6833 (2013.01); A61B 5/685 (2013.01); A61B 5/742 (2013.01); A61B 2010/0006 (2013.01); A61B 2010/0009 (2013.01); A61B 2010/008 (2013.01); A61B 2560/0412 (2013.01)] 28 Claims
OG exemplary drawing
 
1. A wearable device comprising:
microneedles for sampling the interstitial fluid of a user while the device is applied to the user's skin;
a mechanism for detecting the presence or absence of a target substance in the sampled interstitial fluid;
a signaling mechanism for indicating whether or not the target substance was detected in the sampled interstitial fluid; and
a compliance component including an indicator that indicates whether the device has been removed even if the device has been reapplied, wherein the indicator is a portion of the device that undergoes a color change when the device is applied to the user's skin; and
wherein the indicator is visible to the user.