US 11,959,895 B2
Analysis apparatus provided with a plurality of chromatographic apparatuses
Daisuke Akieda, Tokyo (JP); Takayuki Sugime, Tokyo (JP); Izumi Ogata, Tokyo (JP); and Makoto Nogami, Tokyo (JP)
Assigned to HITACHI HIGH-TECH CORPORATION, Tokyo (JP); and ROCHE DIAGNOSTICS OPERATIONS, INC., Indianapolis, IN (US)
Appl. No. 16/961,344
Filed by HITACHI HIGH-TECH CORPORATION, Tokyo (JP); and Roche Diagnostics Operations, Inc., Indianapolis, IN (US)
PCT Filed Nov. 30, 2018, PCT No. PCT/JP2018/044165
§ 371(c)(1), (2) Date Jul. 10, 2020,
PCT Pub. No. WO2019/138725, PCT Pub. Date Jul. 18, 2019.
Claims priority of application No. 2018-002849 (JP), filed on Jan. 11, 2018.
Prior Publication US 2020/0371072 A1, Nov. 26, 2020
Int. Cl. G01N 30/60 (2006.01); G01N 30/24 (2006.01); G01N 30/34 (2006.01); G01N 30/72 (2006.01)
CPC G01N 30/6043 (2013.01) [G01N 30/24 (2013.01); G01N 30/34 (2013.01); G01N 30/7233 (2013.01)] 2 Claims
OG exemplary drawing
 
1. An analysis apparatus provided with a plurality of chromatographic apparatuses and a detector which analyzes a sample, the analysis apparatus comprising:
a multi-chromatographic apparatus including a plurality of liquid chromatographic apparatuses, each of which has a liquid delivery device that delivers a mobile phase to an analysis channel, an injection valve that is connected to the delivery device and introduces a liquid sample into the analysis channel, and a separation column that is connected downstream of the injection valve and separates the sample into respective components;
at least one sample dispensing mechanism which dispenses a sample to the injection valve of the multi-chromatographic apparatus;
a channel switching valve which is connected to each of the separation columns of the multi-chromatographic apparatus and introduces a sample into the detector via an analysis channel, the sample being separated by any of the separation columns of any one of the plurality of chromatographic apparatuses; and
a control unit which controls operations of the multi-chromatographic apparatus, the sample dispensing mechanism, the channel switching valve and the detector,
wherein an analysis section is divided into integral multiple sub-sections which are normalized by a reference time range, and
wherein the control unit is configured to control an introduction operation of the sample into the analysis channel by adding the reference time to operations of the injection valve and the channel switching valve, such that data collection sections of the detector for sample analysis items of each of the plurality of chromatographic apparatuses do not overlap each other and the data collection section for a second analysis item is started after the data collection section of a first analysis item.