CPC C12N 9/48 (2013.01) [A61K 38/48 (2013.01); A61P 1/18 (2018.01)] | 39 Claims |
1. A recombinant protease comprising an amino acid sequence comprising at least 85% sequence identity to SEQ ID NO: 2, wherein the amino acid sequence of the recombinant protease comprises at least a substitution at amino acid position 236, 258, 261, 339, 439, 446, or 450, wherein the amino acid positions are numbered with reference to SEQ ID NO: 2.
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