CPC C07D 401/04 (2013.01) [A61P 31/04 (2018.01); A61P 31/10 (2018.01)] | 7 Claims |
1. A method of making a 3-(4,5-Diphenyl-2-(pyridin-3-yl)-1H-imidazol-1-yl)-N,N-dimethylpropan-1-amine compound having the formula I:
the method comprising:
adding benzil, pyridine-3-carbaldehyde, ammonium acetate, and N,N-Dimethyl-1,3-propanediamine to piperidinium hydrogen sulfate in an oil bath to obtain a reaction mixture;
heating the reaction mixture with stirring until reaction completion to obtain a crude product;
purifying the crude product by recrystallization using absolute ethyl alcohol; and
obtaining the 3-(4,5-Diphenyl-2-(pyridin-3-yl)-1H-imidazol-1-yl)-N,N-dimethylpropan-1-amine compound.
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