US 11,958,829 B1
3-(4,5-diphenyl-2-(pyridin-3-YL)-1H-imidazol-1-YL)-N,N-dimethylpopan-1-amine as an antimicrobial compound
Hany Mohamed Abd El-Lateef Ahmed, Al-Ahsa (SA); Mai M. Khalaf, Al-Ahsa (SA); Antar A. Abdelhamid, Sohag (EG); and Adel A. Marzouk, Cairo (EG)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Dec. 8, 2023, as Appl. No. 18/533,359.
Application 18/533,359 is a division of application No. 18/242,194, filed on Sep. 5, 2023.
Int. Cl. C07D 401/04 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01)
CPC C07D 401/04 (2013.01) [A61P 31/04 (2018.01); A61P 31/10 (2018.01)] 7 Claims
 
1. A method of making a 3-(4,5-Diphenyl-2-(pyridin-3-yl)-1H-imidazol-1-yl)-N,N-dimethylpropan-1-amine compound having the formula I:

OG Complex Work Unit Chemistry
the method comprising:
adding benzil, pyridine-3-carbaldehyde, ammonium acetate, and N,N-Dimethyl-1,3-propanediamine to piperidinium hydrogen sulfate in an oil bath to obtain a reaction mixture;
heating the reaction mixture with stirring until reaction completion to obtain a crude product;
purifying the crude product by recrystallization using absolute ethyl alcohol; and
obtaining the 3-(4,5-Diphenyl-2-(pyridin-3-yl)-1H-imidazol-1-yl)-N,N-dimethylpropan-1-amine compound.