US 11,957,777 B2
Compositions comprising reaction products of saccharide polymers and fatty esters formulated with a neutral surfactant
Christopher P. Gardner, Cresson, TX (US); and Stephen William Almond, Creston, CA (US)
Assigned to INTEGRITY BIO-CHEMICALS, LLC, Cresson, TX (US)
Appl. No. 18/246,151
Filed by INTEGRITY BIO-CHEMICALS, LLC, Cresson, TX (US)
PCT Filed Oct. 26, 2022, PCT No. PCT/US2022/078692
§ 371(c)(1), (2) Date Mar. 21, 2023,
PCT Pub. No. WO2023/076929, PCT Pub. Date May 4, 2023.
Claims priority of provisional application 63/272,368, filed on Oct. 27, 2021.
Prior Publication US 2023/0270654 A1, Aug. 31, 2023
Int. Cl. A61K 8/73 (2006.01); A61K 8/42 (2006.01); A61K 8/92 (2006.01); A61Q 19/00 (2006.01)
CPC A61K 8/73 (2013.01) [A61K 8/42 (2013.01); A61K 8/922 (2013.01); A61Q 19/00 (2013.01); A61K 2800/10 (2013.01); A61K 2800/5422 (2013.01)] 21 Claims
 
1. A composition comprising:
an aqueous phase;
a neutral surfactant or a reaction product form thereof;
a reaction product of a saccharide polymer and a fatty ester, the saccharide polymer comprising a dextran, a dextrin compound, or any combination thereof, and the reaction product of the saccharide polymer and the fatty ester and the reaction product form of the neutral surfactant, if present, being formed in the aqueous phase in the presence of a hydroxide base;
wherein the reaction product form of the neutral surfactant, if present, comprises a fatty ester reaction product formed from a hydroxyl group upon the neutral surfactant; and
one or more alcohols originating from the fatty ester upon forming the reaction product of the saccharide polymer and the fatty ester;
wherein the reaction product of the saccharide polymer and the fatty ester is present in the aqueous phase at a concentration effective to lower a surface tension of the neutral surfactant.