CPC A61K 47/14 (2013.01) [A61K 9/0014 (2013.01); A61K 9/06 (2013.01); A61K 9/107 (2013.01); A61K 9/127 (2013.01); A61K 31/573 (2013.01); A61K 31/58 (2013.01); A61P 17/06 (2018.01)] | 23 Claims |
1. A pharmaceutical composition for topical application to the skin of an individual comprising:
a liquid oil component comprising a dicarboxylic acid ester or a monocarboxylic acid ester, and a mineral oil or a light mineral oil;
a corticosteroid at a concentration of 0.03% or less, wherein the corticosteroid is selected from the group consisting of halobetasol propionate, clobetasol, betamethasone dipropionate, diflorasone diacetate, desoximetasone, mometasone furoate, betamethasone valerate, halcinonide, fluocinonide, and amcinonide, and wherein at least 25% of the corticosteroid is solubilized in the liquid oil component at a temperature of 22° C.±2° C.; and
an aqueous component comprising water;
wherein the pharmaceutical composition does not include white petrolatum; and
wherein the pharmaceutical composition is formulated as a lotion or a cream.
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