US 11,957,709 B2
Oxygen gas sustained released nano-emulsion composition and method for producing the same
Phil June Park, Yongin-si (KR); Jun-pil Jee, Gwangju (KR); Bongsoo Pi, Yongin-si (KR); Haewon Jeong, Yongin-si (KR); Hyoung June Kim, Yongin-si (KR); Dalsu Na, Yongin-si (KR); and Wonseok Park, Yongin-si (KR)
Assigned to AMOREPACIFIC CORPORATION, Seoul (KR); and CHOSUN NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, Gwangju (KR)
Filed by AMOREPACIFIC CORPORATION, Seoul (KR); and CHOSUN NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, Gwangju (KR)
Filed on Jun. 23, 2022, as Appl. No. 17/847,808.
Claims priority of application No. 10-2021-0082583 (KR), filed on Jun. 24, 2021; and application No. 10-2021-0179674 (KR), filed on Dec. 15, 2021.
Prior Publication US 2023/0000902 A1, Jan. 5, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 33/00 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 9/107 (2006.01); A61K 9/16 (2006.01); A61K 9/48 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01); A61K 47/20 (2006.01); A61K 47/24 (2006.01); A61K 47/26 (2006.01); A61K 47/36 (2006.01); A61K 47/38 (2006.01); A61K 47/44 (2017.01); A61P 17/14 (2006.01)
CPC A61K 33/00 (2013.01) [A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 9/0095 (2013.01); A61K 9/06 (2013.01); A61K 9/1075 (2013.01); A61K 9/1617 (2013.01); A61K 9/4858 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/20 (2013.01); A61K 47/24 (2013.01); A61K 47/26 (2013.01); A61K 47/36 (2013.01); A61K 47/38 (2013.01); A61K 47/44 (2013.01); A61P 17/14 (2018.01)] 17 Claims
OG exemplary drawing
 
1. A nanoemulsion composition of oxygen gas sustained release, comprising:
a water phase part containing water; an oil phase part dispersed in the water phase part and made of nanoparticle containing a perfluorocarbon compound;
a main surfactant comprising a fatty acid ester of sorbitan; and
an auxiliary surfactant comprising a fatty acid ester of ethoxylated sorbitan,
wherein the oil phase part contains oxygen gas, and the oxygen gas is released in sustained release,
wherein an average diameter of the nanoparticle is 100 nm to 250 nm, and
wherein a content ratio of the main surfactant and the auxiliary surfactant is 3:1 to 1:1 by weight.