CPC A61K 31/545 (2013.01) [A61K 47/545 (2017.08); A61K 47/60 (2017.08); A61K 47/61 (2017.08); A61K 47/6903 (2017.08); A61P 31/04 (2018.01); A61K 31/546 (2013.01)] | 3 Claims |
1. A diagnostic agent that changes color in response to presence of beta lactamases, wherein the diagnostic agent consists of the following formula:
wherein the maleimide moiety in the structure above facilitates conjugation to a hydrogel forming polymer; further wherein the polymer is not an oligosaccharide; and wherein the diagnostic color change response is from clear to yellow when the B-lactam ring is hydrolyzed, expelling the 4-nitrobenzenethiol leaving group.
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