US 11,957,463 B2
Accuracy of continuous glucose sensors
Boris P. Kovatchev, Charlottesville, VA (US); and Christopher R. King, Chicago, IL (US)
Assigned to ABBOTT DIABETES CARE INC., Alameda, CA (US)
Filed by ABBOTT DIABETES CARE INC., Alameda, CA (US)
Filed on Dec. 20, 2018, as Appl. No. 16/227,910.
Application 16/227,910 is a continuation of application No. 14/799,329, filed on Jul. 14, 2015, granted, now 10,194,850.
Application 14/799,329 is a continuation of application No. 12/065,257, abandoned, previously published as PCT/US2006/033724, filed on Aug. 29, 2006.
Claims priority of provisional application 60/815,191, filed on Jun. 20, 2006.
Claims priority of provisional application 60/713,203, filed on Aug. 31, 2005.
Prior Publication US 2019/0343433 A1, Nov. 14, 2019
Int. Cl. A61B 5/145 (2006.01); A61B 5/00 (2006.01); A61B 5/1495 (2006.01)
CPC A61B 5/1495 (2013.01) [A61B 5/14532 (2013.01); A61B 5/7203 (2013.01); A61B 5/7275 (2013.01); A61B 5/7278 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A method of improving accuracy of an analyte sensor by accounting for a difference caused by a physiological time lag between a blood glucose value and an interstitial fluid glucose value, the method comprising:
receiving raw output from the analyte sensor, wherein the raw output comprises a plurality of data sets;
preprocessing the plurality of data sets;
obtaining an initial calibration of the analyte sensor; and
determining an estimated blood glucose value from the preprocessed plurality of data sets using the initial calibration of the analyte sensor, wherein the estimated blood glucose value is based on one or more interstitial fluid glucose proportionality coefficients and a time derivative of the raw output, wherein the estimated blood glucose value is indicative of a real-time estimated blood glucose value.