	US 12,277,468 B2
	Magnetic bead-based detection method, storage medium, and detection device
Wenwei Zhang, Guangdong (CN); Mei Li, Guangdong (CN); Weimao Wang, Guangdong (CN); Yuxiang Li, Guangdong (CN); and Xun Xu, Guangdong (CN)
Assigned to BGI SHENZHEN, Guangdong (CN)
Filed by BGI SHENZHEN, Guangdong (CN)
Filed on Apr. 30, 2024, as Appl. No. 18/651,099.
Application 18/651,099 is a continuation of application No. PCT/CN2021/127941, filed on Nov. 1, 2021.
Prior Publication US 2024/0281625 A1, Aug. 22, 2024
Int. Cl. G06K 7/08 (2006.01); G01N 33/543 (2006.01); G06T 5/77 (2024.01); G06T 7/00 (2017.01); G06T 7/13 (2017.01); G06T 7/62 (2017.01); G06T 7/73 (2017.01)

CPC G06K 7/087 (2013.01) [G01N 33/54326 (2013.01); G06T 5/77 (2024.01); G06T 7/0002 (2013.01); G06T 7/13 (2017.01); G06T 7/62 (2017.01); G06T 7/73 (2017.01); G06T 2207/10024 (2013.01); G06T 2207/10064 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30204 (2013.01)]

20 Claims

1. A magnetic bead-based detection method, comprising:

collecting a white light image of a to-be-detected solution, wherein a to-be-detected sample and magnetic beads with a capture agent are mixed in the to-be-detected solution;

determining magnetic stripe regions in the white light image;

determining first magnetic bead regions based on the magnetic stripe regions;

selecting, by using a first neural network, second magnetic bead regions containing magnetic beads from the first magnetic bead regions, and obtaining a marker position of each of the magnetic beads;

obtaining, by using a second neural network and based on each of the second magnetic bead regions, codes at code bits of a corresponding magnetic bead; and

obtaining corresponding code information based on the codes at the code bits of the magnetic bead and the marker position of the magnetic bead.