US 12,276,625 B2
Method for species identification and quality detection of liquid-like samples based on nuclear magnetic resonance technology
Yefeng Yao, Shanghai (CN); Jiachen Wang, Shanghai (CN); Yi Li, Shanghai (CN); Jiaxiang Xin, Shanghai (CN); Jing Zhu, Shanghai (CN); and Xuelu Wang, Shanghai (CN)
Assigned to EAST CHINA NORMAL UNIVERSITY, Shanghai (CN)
Appl. No. 17/798,389
Filed by EAST CHINA NORMAL UNIVERSITY, Shanghai (CN)
PCT Filed Apr. 23, 2021, PCT No. PCT/CN2021/089234
§ 371(c)(1), (2) Date Aug. 9, 2022,
PCT Pub. No. WO2021/218798, PCT Pub. Date Nov. 4, 2021.
Claims priority of application No. 202010345962.6 (CN), filed on Apr. 27, 2020.
Prior Publication US 2023/0075079 A1, Mar. 9, 2023
Int. Cl. G01N 24/08 (2006.01); G01N 33/02 (2006.01)
CPC G01N 24/08 (2013.01) [G01N 33/02 (2013.01)] 8 Claims
OG exemplary drawing
 
1. A method for species identification and quality detection of liquid-like samples based on nuclear magnetic resonance technology comprising the following steps:
step 1: designing a pulse sequence that includes pulse block or composite pulses containing 1H spin-echo function and pulse block or composite pulses containing a T1 filter function;
step 2: applying the pulse sequence to the targeted liquid-like samples to obtain their 1H two-dimensional relaxation signals;
step 3: converting the obtained 1H two-dimensional relaxation signals into a fingerprint spectra of the liquid-like samples, to be used for species identification and quality detection of liquid-like samples by obtaining fn(x,y) by normalizing the signal intensity of a two-dimensional relaxation signal f(x,y) and subtracting reference function F(x,y) from fm(x,y), wherein the reference function F(x,y) is obtained from the 1H relaxation properties of the sample, or from a surface fitting of fn(x,y), or averaging Fm(x, y), m=1, 2, . . . , i, which is acquired from surface fitting of the multiple two-dimensional relaxation signals.